FROM ASHEVILLE, NC
Take I-40 west to Exit 27 (US 74, the Great Smoky Mountains Expressway). Continue west on US 74 past Waynesville, Sylva and Dillsboro to Bryson City, Exit 67. The drive from Asheville to Bryson City is approximately one hour.
  
FROM ATLANTA
From West Atlanta, take I-75 north to I-575 north which becomes Georgia route 5. At Blue Ridge, GA, turn left (west) on to Route 60 and travel 1.5 miles to Mineral Bluff, GA. Turn right on to Route "60 Spur" and travel approximately 12 miles to the junction with US 19/74. Turn right (east) and proceed on US 19/74 through Murphy, NC, Andrews, NC and the Nantahala Gorge to Bryson City, Exit 67. The drive from Murphy to Bryson City is approximately one hour, and a total of three hours from downtown Atlanta.
 
From East Atlanta, take I-85 north to I-985 which becomes US 23 which becomes US 23/441.You'll pass through Clayton, GA, Franklin, NC and Dillsboro, NC. Just past Dillsboro, take US 74 (the Great Smoky Mountains Expressway) west to Bryson City, Exit 67. The drive from Atlanta to Bryson City is approximately three hours.
  
FROM CHARLOTTE
Take I-85 west to US 74. Continue west on US 74 to I-26. Go north on I-26 to I-40. Take I-40 west to Exit 27 (US 74, the Great Smoky Mountains Expressway). Continue west on US 74 past Waynesville, Sylva and Dillsboro to Bryson City, Exit 67. The drive from Charlotte to Bryson City is approximately three hours.
 
FROM SPARTANBURG AND GREENVILLE
From Spartanburg, take I-26 north to I-40. Take I-40 west to Exit 27 (US 74, the Great Smoky Mountains Expressway). Continue west on US 74 past Waynesville, Sylva and Dillsboro to Bryson City, Exit 67. The drive from Spartanburg to Bryson City is approximately two hours; or 2-1/2 hours from Greenville.
 
FROM CHATTANOOGA
Take I-75 north to US 64 (Exit 20, near Cleveland, TN). Drive east on US 64 (which becomes US 64/74) through Ducktown, TN and the Ocoee River Gorge into North Carolina. At Murphy, NC take US 19/74 east through Andrews, NC and the Nantahala Gorge to Bryson City, Exit 67. The drive from Chattanooga to Bryson City is approximately three hours.

 
 
FROM KNOXVILLE
You have a choice of four routes from Knoxville:
 
1. Via Interstate 40 - Take I-40 east into North Carolina to exit 27 (US 74, the Great Smoky Mountains Expressway). Continue west on US 74 past Waynesville, Sylva and Dillsboro to Bryson City, Exit 67. The drive from Knoxville to Bryson City is approximately two hours.
 
2. Via US 129 - Take US 129 south through Alcoa and Maryville. After crossing into North Carolina, take US 28 south to US 74 (the Great Smoky Mountains Expressway). Continue east on US 74 approximately 10 miles to Bryson City, Exit 67.
Note: the section of US 129 known as "Deal's Gap" and "The Tail of The Dragon" is extremely curvy (318 curves in 11 miles). The drive from Knoxville to Bryson City is approximately 2-1/2 to three hours
 
3. Via Pigeon Forge and the Great Smoky Mountains National Park - Take I-40 east to exit 407 and proceed south. At Sevierville, TN, take US 441 south through Pigeon Forge, Gatlinburg and the Great Smoky Mountains National Park to Cherokee, NC. At Cherokee, take US 19 south to Bryson City. Depending on traffic, the drive from Knoxville to Bryson City can be from 2-1/2 to four hours.
 
4. Via Townsend and the Great Smoky Mountains National Park - Take US 129 south through Alcoa to Maryville. In Maryville, take US 321 east to Townsend, TN. From Townsend, take Little River Road east through the Great Smoky Mountains National Park to US 441 (at the Park Visitors Center). Take US 441 south through the park to Cherokee, NC. At Cherokee, take US 19 south to Bryson City. Depending on traffic, the drive from Knoxville to Bryson City is approximately three hours.

IN BRYSON CITY...

TO WEST OAK B&B and CABINS — After exiting US 74 at exit 72, go north on Veterans Blvd. Turn right on Academy Street. Turn right on Fryemont Road. After the road curves to your right, West Oak will be on your left.

TO THE VACATION RENTALS— Take US 74 to Exit 64 (Alarka). At the south end of the overpass bridge, turn east on to Brendle Road. After the pavement ends, take the left fork and you will soon enter Fox Run Ridge. Continue up the mountain until you see the sign for Oak Hill. For Treetop, continue past Oak Hill to 864 Fox Run Ridge Road. For Windsong, continue past Treetop and turn right on Kahn Trail. Windsong is at the end of Kahn Trail (Number 250).